Surface Activated Chemical Ionization in the analysis of addicted drugs in human hairs by acid hydrolysis and sample dilution

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چکیده

Drugs abuse is a serious issue in our modern society and a sensible approach to detect it is necessary. Hair analysis can show the presence of addict drugs in the body even after many days since the time of assumption. Actually, solid phase extraction (SPE) approaches are necessary due to the low legally mandated cut-off to be detected for the analysis to be considered valid; In this work a new liquid ionization source, Surface-Activated Chemical Ionization (SACI), has been coupled to Brukler Daltonics’ Esquire 3000 mass spectrometer to analyze. Cocaine and Benzoyletgonine extracted from human hair without using SPE but simply diluting the 10 times the extracted solution.

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تاریخ انتشار 2007